Scientists can reverse the aging process in mice

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Scientists found a way to protect DNA in mice from the deterioration that appears with aging and they are ready to test this on humans.

Doctor David Sinclair from Harvard, along with his colleagues, studied a compound that has rejuvenation abilities called NAD+ (a coenzyme that can be found in all living things ). They discovered that NAD+ is a compound that can be found in larger quantity in younger mice, but in smaller quantity in older mice. Considering this, specialists increased the level of the substance in the bodies of adult mice and discovered that they appear to be much younger.

In the last study, researchers reveal new details regarding the way NAD+ acts to keep cells young. They placed NAD+ drops in the water of a group of mice and in just a few hours of level of this enzyme started to grow. In the first week scientists noticed serious changes in the body of the mice ( regarding muscular repair and DNA ). The changes were so substantial that scientists were unable to tell the difference between a two years old mouse and a three or four months old mouse, which proves that these mice got younger.

Basically, the effects of aging can be delayed because NAD+ is connected with the DNA repair feature and ensures it. Every time cells divide, the DNA gets copied, but it is not always a perfect process and sometimes errors happen ( especially with an aging body ) that affects this organic substance. Normally, most problems can be repaired as long as the DNA contains the compound responsible with this – PARP1 – and this can do what is supposed to do only when the NAD+ quantity in the body is big enough.

However although it is noticed that the NAD+ level has positive effects in mice, it remains to be seen if it will have the same effects on human bodies. The study conducted by Doctor Sinclair is co-funded by a company called MetroBiotech to develop and test this on humans too.

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